Shandong A Group Co., Ltd. purchases crosslinked polyvilone super fine mill Cum260-F

General introduction

　　A Group Co., Ltd., Shandong, was established in November 2011. It is a joint-stock company for pharmaceutical and new accessories, research and development, sales, located in the hinterland of the high-efficiency ecological economic zone of the Yellow River Delta, located in the country. County, east to Dongqing Expressway, west, Hexin Road, North 319 provincial road, position and surrounding environment, convenient transportation.

　　The company introduced advanced technology developed by Tsinghua University and Xiamen University, identified the annual output of 14,000 tons of polyvinylpyrrolidone (PVP) pharmaceutical new excipient product project. The project covers an area of ​​242 mu, with a total investment of 520 million yuan, and the overall construction cycle is 3 years; one of the first phases of investment of 360 million yuan, the annual output of 7,000 tons (PVP) medicinal accessories, the completion of the production, the annual output is completed in 2012 1 billion yuan, profit tax is 150 million yuan, which is the largest PVP production, sales and export enterprises in the province. The construction facilities include: AP production workshop, PVP production workshop, raw tank area, finished warehouse, raw material warehouse, centralized control room integrated building, scientific research complex, employee restaurant, staff dormitory building, sewage treatment station, frozen station and fire Buildings such as systems.

　　Crosslinked polyverene introduction:

　　Crosslinked polymethone, medicinal accessories, is an insoluble synthetic crosslinker N-vinyl-2-pyrrolidone homopolymer . Due to the insoluble material of the material itself, the exact molecular weight is not yet determined. This product is white or white powder; almost odorless; humidification. This product is insoluble in water, ethanol, trichloromethane or diethyl ether. This product has a high capillary / water-containing capacity, larger surface, high hydration capacity (HK: 5.6), high absorption, rapid (58.5%), strong water absorption, 2.25-2.30, with polyethylene The same complexing capacity of pyrrolidone can be complexed with a variety of substances such as phenols, iodine, and the like.

　　Crosslinked Polymethone is a water-insoluble tablet disintegrant, which can quickly exhibit high capillary activity and excellent hydrational ability, and the tendency of almost no gel; studies have shown that cross-linking gathering The size of the ketone particles strongly affects the disintegration of the antipyretic sedent, and the particle large crosslinked polyvantone is relatively small to play a faster disintegration. Crosslinner is a very excellent disintegrant, and the amount of commonly used commonly disintegrant can be obtained in the tablet, and it is known as super-disintegrant. Crosslinked polyvidone can also be a pieceDry binders, fillers, and excipients of the capsule, a capsule, a small particle size, can reduce the strip of the tablet in the tablet, improve the uniformity of the tablet, and the common amount is 20-80 mg. /piece. Crosslinked polyvilone can also be used as a dissolution accelerator, using a co-evaporation technique, can increase the solubility of the difficult-soluble drug: first adsorb the drug to the crosslinked polyitone, then evaporate the solvent, this technology can Get faster dissolution speed.